Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
faculty of Sciences, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
Three new neutral complexes of copper(II) containing chalcone ligands derived from 2'-hydoxyacetophenone and 4-substituted benzaldehydes were synthesized. Complexes were prepared by solution synthesis and characterized by spectroscopy. The catalytic activity of complexes was examined in the reaction of 3,5-di-tertbutylcatehcol (DTBC) oxidation. The kinetics of DTBC catalytic oxidation by copper(II) complexes (1 – 3) was investigated spectrophotometrically under pseudo-first-order conditions. Catalytic parameters, the maximum reaction rate (vmax), Michaelis-Menten constant (KM), catalytic efficiency, catalytic reaction rate constant (kcat), turnover number (TON), and turnover frequencies (TOF) for complexes 1 – 3 in DTBC oxidation were collected. The studied complexes 1 and 2 were found to have moderate catalytic activity, while complex 3 does not show catalytic properties.
[{"id":150,"citationNumber":null,"type":"article-journal","title":"The crystal structure of catechol oxidase: new insight into the function of type-3 copper proteins","DOI":null,"author":[{"given":"C.","family":"Gerdemann"},{"given":"C.","family":"Eicken"},{"given":"B.","family":"Krebs"}],"issued":{"date-parts":["2002"]},"container-title":"Accounts of chemical research","volume":"35","issue":null,"page":"183\u2013191"}]
[{"id":151,"citationNumber":null,"type":"article-journal","title":"Synthetic models of the active site of catechol oxidase: mechanistic studies","DOI":null,"author":[{"given":"I.A.","family":"Koval"},{"given":"P.","family":"Gamez"},{"given":"C.","family":"Belle"},{"given":"L.","family":"Selmeczi"},{"given":"J.","family":"Reedijk"}],"issued":{"date-parts":["2006"]},"container-title":"Chemical Society Reviews","volume":"35","issue":null,"page":"814\u2013840"}]
[{"id":152,"citationNumber":null,"type":"article-journal","title":"Catalytic catechol oxidation by copper complexes: development of a structureactivity relationship","DOI":null,"author":[{"given":"E.C.","family":"Ording-Wenker"},{"given":"M.A.","family":"Siegler"},{"given":"M.","family":"Lutz"},{"given":"E.","family":"Bouwman"}],"issued":{"date-parts":["2015"]},"container-title":"Dalton Transactions","volume":"44","issue":null,"page":"12196\u201312209"}]
[{"id":153,"citationNumber":null,"type":"article-journal","title":"Catalytic fate of two copper complexes towards phenoxazinone synthase and catechol dioxygenase activity","DOI":null,"author":[{"given":"M.","family":"Garai"},{"given":"D.","family":"Dey"},{"given":"H.R.","family":"Yadav"},{"given":"A.R.","family":"Choudhury"},{"given":"M.","family":"Maji"},{"given":"B.","family":"Biswas"}],"issued":{"date-parts":["2017"]},"container-title":"ChemistrySelect","volume":"2","issue":null,"page":"11040\u201311047"}]
[{"id":154,"citationNumber":null,"type":"article-journal","title":"Copper (II)- catalyzed oxidation of catechol by molecular oxygen in aqueous solution","DOI":null,"author":[{"given":"J.","family":"Balla"},{"given":"T.","family":"Kiss"},{"given":"R.F.","family":"Jameson"}],"issued":{"date-parts":["1992"]},"container-title":"Inorganic Chemistry","volume":"31","issue":null,"page":"58\u201362"}]
[{"id":155,"citationNumber":null,"type":"article-journal","title":"Catechol oxidase activity of dicopper complexes with N-donor ligands","DOI":null,"author":[{"given":"K.","family":"Selmeczi"},{"given":"M.","family":"R\u00e9glier"},{"given":"M.","family":"Giorgi"},{"given":"G.","family":"Speier"}],"issued":{"date-parts":["2003"]},"container-title":"Coordination chemistry reviews","volume":"245","issue":null,"page":"191\u2013201"}]
[{"id":156,"citationNumber":null,"type":"article-journal","title":"Functional mimics of catechol oxidase by mononuclear copper complexes of sterically demanding [NNO] ligands","DOI":null,"author":[{"given":"M.K.","family":"Panda"},{"given":"M.M.","family":"Shaikh"},{"given":"R.J.","family":"Butcher"},{"given":"P.","family":"Ghosh"}],"issued":{"date-parts":["2011"]},"container-title":"Inorganica Chimica Acta","volume":"372","issue":null,"page":"145\u2013151"}]
[{"id":157,"citationNumber":null,"type":"article-journal","title":"Tuning the activity of catechol oxidase model complexes by geometric changes of the dicopper core","DOI":null,"author":[{"given":"J.","family":"Ackermann"},{"given":"F.","family":"Meyer"},{"given":"Kaifer","family":"E."},{"given":"H.","family":"Pritzkow"}],"issued":{"date-parts":["2002"]},"container-title":"Chemistry\u2013A European Journal","volume":"8","issue":null,"page":"247\u2013258"}]
[{"id":158,"citationNumber":null,"type":"article-journal","title":"Recent progress in synthesis and characterization of metal chalcone complexes and their potential as bioactive agents","DOI":null,"author":[{"given":"C.","family":"Sulpizio"},{"given":"J.","family":"Breibeck"},{"given":"A.","family":"Rompel"}],"issued":{"date-parts":["2018"]},"container-title":"Coordination Chemistry Reviews","volume":"373","issue":null,"page":"497\u2013524"}]
[{"id":159,"citationNumber":null,"type":"article-journal","title":"Antiobesity, antioxidant and cytotoxicity activities of newly synthesized chalcone derivatives and their metal complexes","DOI":null,"author":[{"given":"M.R.E.S.","family":"Aly"},{"given":"H.H.A.E.R.","family":"Fodah"},{"given":"S.Y.","family":"Saleh"}],"issued":{"date-parts":["2014"]},"container-title":"European Journal of medicinal chemistry","volume":"76","issue":null,"page":"517\u2013530"}]
[{"id":160,"citationNumber":null,"type":"article-journal","title":"Cytotoxic activity, albumin and DNA binding of new copper (II) complexes with chalconederived thiosemicarbazones","DOI":null,"author":[{"given":"J.G.","family":"Silva"},{"given":"A.A.R.","family":"Despaigne"},{"given":"S.R.","family":"Louro"},{"given":"C.C.","family":"Bandeira"},{"given":"E.M.","family":"Souza-Fagundes"},{"given":"H.","family":"Beraldo"}],"issued":{"date-parts":["2013"]},"container-title":"European Journal of Medicinal Chemistry","volume":"65","issue":null,"page":"415\u201326"}]
[{"id":161,"citationNumber":null,"type":"article-journal","title":"Synthesis, characterization, and antioxidant activity of Zn 2+ and Cu 2+ coordinated polyhydroxy chalcone complexes","DOI":null,"author":[{"given":"C.","family":"Sulpizio"},{"given":"S.T.","family":"M\u00fcller"},{"given":"Q.","family":"Zhang"},{"given":"L.","family":"Brecker"},{"given":"A.","family":"Rompel"}],"issued":{"date-parts":["2016"]},"container-title":"Monatshefte f\u00fcr Chemie-Chemical Monthly","volume":"147","issue":null,"page":"1871\u20131881"}]
[{"id":162,"citationNumber":null,"type":"article-journal","title":"Antiviral activity of substituted chalcones and their respective Cu (ii), Ni (ii) and Zn (ii) complexes","DOI":null,"author":[{"given":"K.","family":"Mallikarjun"}],"issued":{"date-parts":["2005"]},"container-title":"E-Journal of Chemistry","volume":"2","issue":null,"page":"58\u201361"}]
[{"id":163,"citationNumber":null,"type":"article-journal","title":"Synthesis, Xray crystal structures and catecholase activity investigation of new chalcone ligands","DOI":null,"author":[{"given":"S.","family":"Thabti"},{"given":"A.","family":"Djedouani"},{"given":"S.","family":"Rahmouni"},{"given":"R.","family":"Touzani"},{"given":"A.Bendaas","family":"R."},{"given":"H.","family":"Mousser"},[]],"issued":{"date-parts":["2015"]},"container-title":"Journal Of Molecular Structure","volume":"1102","issue":null,"page":"295\u2013301"}]
[{"id":164,"citationNumber":null,"type":"article-journal","title":"Synthesis, magnetostructural correlation, and catalytic promiscuity of unsymmetric dinuclear copper (II) complexes: Models for catechol oxidases and hydrolases","DOI":null,"author":[{"given":"R.E.","family":"Os\u00f3rio"},{"given":"R.A.","family":"Peralta"},{"given":"A.J.","family":"Bortoluzzi"},{"given":"V.R.","family":"Almeida"},{"given":"B.","family":"Szpoganicz"},{"given":"F.L.","family":"Fischer"},[]],"issued":{"date-parts":["2012"]},"container-title":"Inorganic chemistry","volume":"51","issue":null,"page":"1569\u20131589"}]
[{"id":165,"citationNumber":null,"type":"article-journal","title":"Chalcone and Flavonol Copper (II) Complexes Containing Schiff Base Co-Ligand: Synthesis, Crystal Structures and Catecholase-like Activity","DOI":null,"author":[{"given":"E.","family":"Kahrovi\u0107"},{"given":"A.","family":"Zahirovi\u0107"},{"given":"A.","family":"Vi\u0161njevac"},{"given":"I.","family":"Osmankovi\u0107"},{"given":"E.","family":"Turku\u0161i\u0107"},{"given":"H.","family":"Kurtagi\u0107"}],"issued":{"date-parts":["2018"]},"container-title":"Croatica Chemica Acta","volume":"91","issue":null,"page":"195\u2013208"}]
[{"id":166,"citationNumber":null,"type":"article-journal","title":"Chalcone synthesis, properties and medicinal applications: a review","DOI":null,"author":[{"given":"A.","family":"Rammohan"},{"given":"J.S.","family":"Reddy"},{"given":"G.","family":"Sravya"},{"given":"C.N.","family":"Rao"},{"given":"G.V.","family":"Zyryanov"}],"issued":{"date-parts":["2020"]},"container-title":"Environmental Chemistry Letters","volume":"18","issue":null,"page":"433\u2013458"}]
[{"id":167,"citationNumber":null,"type":"article-journal","title":"Mononuclear Cu (II) complex of an oxime ligand derived from N-Heterocyclic hydrazide: Synthesis, spectroscopy, electrochemistry, DFT calculations, and catecholase activity","DOI":null,"author":[{"given":"A.","family":"Zengin"},{"given":"K.","family":"Karao\u011flu"},{"given":"M.","family":"Emirik"},{"given":"E.","family":"Mente\u015fe"},{"given":"K.","family":"Serbest"}],"issued":{"date-parts":["2019"]},"container-title":"Journal of Molecular Structure","volume":"1193","issue":null,"page":"444\u2013449"}]
[{"id":168,"citationNumber":null,"type":"article-journal","title":"Chalconoid metal chelates: spectral, biological and catalytic applications","DOI":null,"author":[{"given":"J.","family":"Johnson"},{"given":"A.","family":"Yardily"}],"issued":{"date-parts":["2019"]},"container-title":"Journal of Coordination Chemistry","volume":"72","issue":null,"page":"2437\u20132488"}]
[{"id":169,"citationNumber":null,"type":"article-journal","title":"Solvent dependent ligand transformation in a dinuclear copper (II) complex of a compartmental Mannichbase ligand: synthesis, characterization, biorelevant catalytic promiscuity and magnetic study","DOI":null,"author":[{"given":"I.","family":"Majumder"},{"given":"P.","family":"Chakraborty"},{"given":"S.","family":"Das"},{"given":"H.","family":"Kara"},{"given":"S.K.","family":"Chattopadhyay"},{"given":"E.","family":"Zangrando"},[]],"issued":{"date-parts":["2015"]},"container-title":"RSC Advances","volume":"5","issue":null,"page":"51290\u201351301"}]
[{"id":170,"citationNumber":null,"type":"article-journal","title":"Catechol oxidase activity of dinuclear copper (II) complexes of Robson type macrocyclic ligands: Syntheses, X-ray crystal structure, spectroscopic characterization of the adducts and kinetic studies","DOI":null,"author":[{"given":"K.S.","family":"Banu"},{"given":"T.","family":"Chattopadhyay"},{"given":"A.","family":"Banerjee"},{"given":"S.","family":"Bhattacharya"},{"given":"E.","family":"Zangrando"},{"given":"D.","family":"Das"}],"issued":{"date-parts":["2009"]},"container-title":"Journal of Molecular Catalysis A: Chemical","volume":"310","issue":null,"page":"34\u201341"}]
[{"id":171,"citationNumber":null,"type":"article-journal","title":"Design of a mononuclear copper (II)- phenanthroline complex: Catechol oxidation, DNA cleavage, and antitumor properties","DOI":null,"author":[{"given":"D.","family":"Dey"},{"given":"S.","family":"Das"},{"given":"H.R.","family":"Yadav"},{"given":"A.","family":"Ranjani"},{"given":"L.","family":"Gyathri"},{"given":"S.","family":"Roy"}],"issued":{"date-parts":["2016"]},"container-title":"Polyhedron","volume":"106","issue":null,"page":"106\u2013114"}]
[{"id":172,"citationNumber":null,"type":"article-journal","title":"Influence of anionic co-ligands on the structural diversity and catecholase activity of copper (II) complexes with 2-methoxy-6- (8-iminoquinolinylmethyl) phenol","DOI":null,"author":[{"given":"M.","family":"Shyamal"},{"given":"T.K.","family":"Mandal"},{"given":"A.","family":"Panja"},{"given":"A.","family":"Saha"}],"issued":{"date-parts":["2014"]},"container-title":"RSC advances","volume":"4","issue":null,"page":"53520\u201353530"}]
Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. 
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.